Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
2301 |
EN300-158082_1_1
|
|
CC1(CN(C[C@@H](O1)CO)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)C |
−9.9
± 0.4
|
7.2
± 0.3
|
2302 |
EN300-76841_3_2
|
|
C[C@](COC)(C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−9.9
± 0.4
|
7.2
± 0.3
|
2303 |
MIC-UNK-67d4a29a-1
|
|
CN(c1cncc2c1c(ccc2)Cl)C(=O)Cc3cccc(c3)Cl |
−9.9
± 0.2
|
7.2
± 0.2
|
2304 |
EDJ-MED-d203f206-43
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC[C@@H](C5)O |
−9.9
± 0.3
|
7.2
± 0.2
|
2305 |
DAR-DIA-0d514e7d-6_1
|
|
C[C@H]1COc2c(cc(cc2OC3CC3)Cl)[C@@H]1C(=O)Nc4cncc5c4cccc5 |
−9.9
± 0.2
|
7.2
± 0.1
|
2306 |
EN300-159633_1_2
|
|
C[C@](C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)(C(F)(F)F)O |
−9.9
± 0.2
|
7.2
± 0.2
|
2307 |
EN300-102007_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCO[C@@H](C5)CCO |
−9.9
± 0.3
|
7.2
± 0.2
|
2308 |
EN300-7412943_1_1
|
|
CC1(CN(C[C@@H](O1)CO)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)C |
−9.9
± 0.4
|
7.2
± 0.3
|
2309 |
EDJ-MED-d203f206-20
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)Nc5ncncn5 |
−9.8
± 0.3
|
7.2
± 0.2
|
2310 |
EN300-207959_1_2
|
|
C[C@]1(CCNC1=O)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.3
|
7.2
± 0.3
|
2311 |
EN300-216673_1_1
|
|
Cn1c(cnn1)CO[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.2
|
7.2
± 0.2
|
2312 |
EN300-177118_1_2
|
|
C[C@]1(CCC(=O)N1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.2
|
7.2
± 0.2
|
2313 |
EDJ-MED-fcba3f31-12
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCc5n[nH]c(=O)s5 |
−9.8
± 0.2
|
7.2
± 0.2
|
2314 |
EN300-182725_1_3
|
|
C[C@@H]([C@H](C)S(=O)(=O)C)C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.8
± 0.3
|
7.2
± 0.2
|
2315 |
EN300-254121_1_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@H](c5cnc[nH]5)O |
−9.8
± 0.4
|
7.2
± 0.3
|
2316 |
EN300-2007627_1_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5C[C@H](C[C@@H](C5)CO)CO |
−9.8
± 0.4
|
7.2
± 0.3
|
2317 |
EDG-MED-90036822-51
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C(CCF)O |
−9.8
± 0.2
|
7.2
± 0.2
|
2318 |
EN300-1708848_1_1
|
|
C[C@@H]([C@@H]1CN(CCO1)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−9.8
± 0.4
|
7.2
± 0.3
|
2319 |
EN300-154156_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(=O)NC5 |
−9.8
± 0.2
|
7.2
± 0.2
|
2320 |
EN300-6779469_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5[C@@H]6[C@@H]5CS(=O)(=O)C6 |
−9.8
± 0.2
|
7.2
± 0.2
|
2321 |
EN300-817811_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cc(=O)[nH]cn5 |
−9.8
± 0.2
|
7.2
± 0.1
|
2322 |
EN300-207765_1_1
|
|
CN1[C@@H](CCC1=O)CC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.3
|
7.2
± 0.2
|
2323 |
EN300-7183657_1_1
|
|
CC1(CC(C1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−9.8
± 0.2
|
7.2
± 0.2
|
2324 |
EN300-6736413_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CO[C@@H]5CCNC5=O |
−9.8
± 0.2
|
7.2
± 0.1
|
2325 |
EN300-6764450_2_1
|
|
CNC(=O)N1CCC(CC1)NC(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.3
|
7.2
± 0.2
|
2326 |
RAL-THA-2d450e86-17
|
|
c1ccc2c(c1)cncc2NC(=O)Cc3cc(cc(c3)Cl)C#N |
−9.8
± 0.3
|
7.2
± 0.2
|
2327 |
ED_-GRI-5b13fbe2-37
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCc5cn(nn5)C[C@@H]6CCCN6 |
−9.8
± 0.3
|
7.2
± 0.2
|
2328 |
EN300-95698_1_4
|
|
C[C@H]1CC(=O)NC[C@H]1C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.2
|
7.2
± 0.2
|
2329 |
EN300-761746_3_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCc5c(=O)[nH]c(=O)[nH]n5 |
−9.8
± 0.3
|
7.2
± 0.2
|
2330 |
EN300-227055_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C[C@@H]5CC(=O)NC5=O |
−9.8
± 0.3
|
7.2
± 0.2
|
2331 |
EN300-250836_3_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CCc5c[nH]nc5 |
−9.8
± 0.3
|
7.2
± 0.2
|
2332 |
FRA-DIA-13af2da5-2_1
|
|
CN(C)c1ccc(cc1)[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.2
|
7.2
± 0.2
|
2333 |
EDG-MED-ba1ac7b9-3
|
|
c1ccc2c(c1)cncc2NC(=O)C3(CCOc4c3cc(cc4)Cl)CC(=O)N(CCO)C5CC5 |
−9.8
± 0.3
|
7.2
± 0.2
|
2334 |
KAD-UNI-8a629cb0-24
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CC6(C5)CS(=O)(=O)C6 |
−9.8
± 0.3
|
7.2
± 0.2
|
2335 |
ALF-EVA-0b412456-1
|
|
c1cc2cncc(c2cc1Cl)NC(=O)Cc3cc(cc(c3)Cl)OC4CC(=O)N4 |
−9.8
± 0.3
|
7.2
± 0.2
|
2336 |
KAD-UNI-8a629cb0-29
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOC[C@@H]5CC6(CC6)S(=O)(=O)N5 |
−9.8
± 0.3
|
7.2
± 0.2
|
2337 |
DAR-DIA-6be260fc-2
|
|
CC(C)C[C@H]1CN(C(=O)C12CNc3c2cc(cc3)Cl)c4cncc5c4cccc5 |
−9.8
± 0.3
|
7.2
± 0.2
|
2338 |
EN300-306316_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCc5[nH]ncn5 |
−9.8
± 0.2
|
7.2
± 0.1
|
2339 |
EN300-862647_3_1
|
|
C[C@@H](C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)NC(=O)C |
−9.8
± 0.3
|
7.2
± 0.2
|
2340 |
ALP-UNI-3496895b-9
|
|
CN(C1CCN(CC1)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)S(=O)(=O)C |
−9.8
± 0.3
|
7.2
± 0.2
|
2341 |
EN300-124973_1_1
|
|
Cc1cc(=O)n2c(n1)N(CC2)C(=O)C[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−9.8
± 0.2
|
7.2
± 0.2
|
2342 |
EN300-132624_3_1
|
|
CCC(=O)CNC(=O)COCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.8
± 0.3
|
7.2
± 0.2
|
2343 |
EN300-91609_1_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCO[C@H]6[C@H]5C6 |
−9.8
± 0.3
|
7.2
± 0.2
|
2344 |
EN300-132963_1_1
|
|
CN1[C@@H](CCC1=O)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.3
|
7.2
± 0.2
|
2345 |
EN300-05277_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CCC(=O)N5CCOCC5 |
−9.8
± 0.3
|
7.2
± 0.2
|
2346 |
EN300-138170_1_1
|
|
C[C@@H]1CCN(C1)C(=O)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.3
|
7.2
± 0.2
|
2347 |
EN300-11195_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC(=O)N5CCC5 |
−9.8
± 0.2
|
7.2
± 0.2
|
2348 |
EN300-761618_3_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCC(=O)Nc5cccnn5 |
−9.8
± 0.3
|
7.2
± 0.2
|
2349 |
EN300-13890_3_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CS[C@H]5CCS(=O)(=O)C5 |
−9.8
± 0.3
|
7.2
± 0.2
|
2350 |
EN300-123489_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C(CO)(F)F |
−9.8
± 0.2
|
7.2
± 0.2
|
2351 |
EN300-1704404_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@@H]5CNC(=O)CC56CCC6 |
−9.8
± 0.2
|
7.2
± 0.2
|
2352 |
EN300-6478631_3_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@H]5CCCc6n5cnn6 |
−9.8
± 0.3
|
7.2
± 0.2
|
2353 |
EN300-11441_3_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cc5cc(=O)[nH]c(=O)[nH]5 |
−9.8
± 0.3
|
7.2
± 0.2
|
2354 |
EN300-95698_1_1
|
|
C[C@@H]1CC(=O)NC[C@@H]1C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.2
|
7.2
± 0.2
|
2355 |
EN300-40947_1_2
|
|
C[C@H](C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)S(=O)(=O)C(C)C |
−9.8
± 0.3
|
7.2
± 0.2
|
2356 |
EN300-154912_1_1
|
|
COc1nccc(n1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.3
|
7.2
± 0.2
|
2357 |
EN300-66461_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@@H]5CNC(=O)N5 |
−9.8
± 0.2
|
7.2
± 0.1
|
2358 |
EN300-7355737_3_1
|
|
Cn1cc(c(n1)COCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)S(=O)(=O)N |
−9.8
± 0.4
|
7.2
± 0.3
|
2359 |
EN300-204935_3_1
|
|
Cn1ncc(n1)C(=O)COCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.3
|
7.2
± 0.2
|
2360 |
LAU-MED-88a3970a-1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@H]3CCOc4c3cc(cc4OCCO)Cl |
−9.8
± 0.2
|
7.2
± 0.2
|
2361 |
EN300-1911992_2_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COC[C@H]([C@H]5CCOC5)O |
−9.8
± 0.3
|
7.2
± 0.2
|
2362 |
EN300-6478054_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCOC[C@@H](C5)CO |
−9.8
± 0.4
|
7.2
± 0.3
|
2363 |
EN300-64536_1_1
|
|
COCCC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.8
± 0.2
|
7.2
± 0.2
|
2364 |
EN300-31553_3_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CCS(=O)(=O)N |
−9.8
± 0.3
|
7.2
± 0.3
|
2365 |
EDJ-MED-28ec730d-4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCc5c[nH]nc5 |
−9.8
± 0.2
|
7.2
± 0.2
|
2366 |
EN300-189563_4_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCCC5CS(=O)(=O)C5 |
−9.8
± 0.3
|
7.2
± 0.2
|
2367 |
EN300-321790_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5C[C@@H]6C[C@H]5CO6 |
−9.8
± 0.2
|
7.2
± 0.2
|
2368 |
EN300-196140_1_2
|
|
C[C@]1(CCN(C1)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)C(=O)NC |
−9.8
± 0.4
|
7.2
± 0.3
|
2369 |
EN300-301690_1_2
|
|
CS(=O)(=O)[N@]1CC[C@H](C1)O[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.3
|
7.2
± 0.2
|
2370 |
EN300-310888_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCc5nnc6n5CCOCC6 |
−9.8
± 0.3
|
7.2
± 0.2
|
2371 |
EDJ-MED-fcba3f31-1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CO[C@@H]5CCCNC5=O |
−9.8
± 0.2
|
7.2
± 0.2
|
2372 |
EN300-05620_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CCCNC(=O)N |
−9.8
± 0.3
|
7.2
± 0.2
|
2373 |
EN300-179091_3_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)COC(F)F |
−9.8
± 0.2
|
7.2
± 0.2
|
2374 |
EN300-205486_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)Cc5c[nH]ccc5=O |
−9.8
± 0.3
|
7.2
± 0.2
|
2375 |
EN300-1644723_4_6
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)[C@H]5[C@@H]6[C@H]5COCC6 |
−9.8
± 0.4
|
7.2
± 0.3
|
2376 |
EN300-262604_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)Cn5cnc(n5)C(=O)N |
−9.8
± 0.4
|
7.2
± 0.3
|
2377 |
EN300-214800_4_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCCN5CCNC5=O |
−9.8
± 0.3
|
7.2
± 0.2
|
2378 |
EDG-MED-90036822-60
|
|
CC(C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)n5ccnc5 |
−9.8
± 0.2
|
7.2
± 0.1
|
2379 |
EN300-307053_1_1
|
|
CC(=O)Nc1cc(c(=O)[nH]c1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.3
|
7.2
± 0.2
|
2380 |
EN300-120562_1_3
|
|
C[C@@H]1C[N@@H+]2CC[N@H+]1[C@H](C2)C(=O)N[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−9.8
± 0.3
|
7.2
± 0.2
|
2381 |
EN300-6494158_4_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOC[C@H]5C[C@H](CO5)CO |
−9.8
± 0.3
|
7.2
± 0.2
|
2382 |
EN300-18249_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC(=O)N |
−9.8
± 0.2
|
7.2
± 0.1
|
2383 |
EN300-1600517_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COC[C@@H](CO)F |
−9.8
± 0.3
|
7.2
± 0.2
|
2384 |
EN300-7535922_1_1
|
|
CN(C)c1ccc(nn1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.2
|
7.2
± 0.1
|
2385 |
EN300-6745214_1_1
|
|
CONC1CN(C1)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.2
|
7.2
± 0.2
|
2386 |
ALP-POS-477dc5b7-5
|
|
c1ccc2c(c1)cncc2N3CCCC4(C3=O)CCOc5c4cc(cc5)Cl |
−9.8
± 0.3
|
7.1
± 0.2
|
2387 |
EN300-14458_2_2
|
|
C[C@H](C(=O)N(C)C)OC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.8
± 0.2
|
7.1
± 0.2
|
2388 |
EN300-246248_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COC[C@@H]5CCNC5=O |
−9.8
± 0.2
|
7.1
± 0.2
|
2389 |
EN300-151461_2_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cn(nn5)[C@H]6CCOC6 |
−9.8
± 0.4
|
7.1
± 0.3
|
2390 |
EN300-6479181_3_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@H]5CC[C@@H]6N5C(=O)CC6 |
−9.8
± 0.3
|
7.1
± 0.2
|
2391 |
EN300-92662_1_1
|
|
Cn1c(ccn1)CCC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.2
|
7.1
± 0.2
|
2392 |
EN300-153257_1_2
|
|
CC(C)[C@H](CO)C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.8
± 0.2
|
7.1
± 0.2
|
2393 |
EN300-97904_3_1
|
|
CS(=O)(=O)CC1(CC1)CC(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.3
|
7.1
± 0.2
|
2394 |
EN300-261596_1_1
|
|
C=CCn1cc(nn1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.2
|
7.1
± 0.2
|
2395 |
EN300-1253178_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC(=O)NC5CC5 |
−9.8
± 0.3
|
7.1
± 0.2
|
2396 |
EN300-72109_1_1
|
|
CC(C)(C)OC(=O)N[C@@H](CO)C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.8
± 0.3
|
7.1
± 0.2
|
2397 |
EN300-268198_2_2
|
|
C[C@H](CC(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)NC(=O)N |
−9.8
± 0.2
|
7.1
± 0.1
|
2398 |
EN300-220676_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C[C@@H]5CCCS(=O)(=O)C5 |
−9.8
± 0.2
|
7.1
± 0.2
|
2399 |
EN300-1718675_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cnnn5C6CC6 |
−9.8
± 0.3
|
7.1
± 0.2
|
2400 |
EN300-67573_3_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCC(=O)NC5CCOCC5 |
−9.8
± 0.3
|
7.1
± 0.2
|