Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
1701 |
ALP-UNI-76695c4f-8
|
|
CN(C1CCN(CC1)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)S(=O)(=O)C |
−10.2
± 0.2
|
7.4
± 0.2
|
1702 |
EN300-1387145_1_4
|
|
CS(=O)(=O)[C@H]1CCC[C@H]1C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.3
|
7.4
± 0.2
|
1703 |
EN300-252260_1_1
|
|
COc1cc(cnn1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.2
|
7.4
± 0.2
|
1704 |
EN300-113218_4_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CS[C@@H]5CCOC5=O |
−10.2
± 0.4
|
7.4
± 0.3
|
1705 |
EN300-6238494_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC(=O)[C@@H]5COCCO5 |
−10.2
± 0.3
|
7.4
± 0.2
|
1706 |
EN300-139167_3_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOC[C@H]5COCCO5 |
−10.2
± 0.2
|
7.4
± 0.1
|
1707 |
EN300-53423_1_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@H]5CCOC5 |
−10.2
± 0.3
|
7.4
± 0.2
|
1708 |
EN300-83918_1_1
|
|
CC(C)[C@@H](C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)NC(=O)COC |
−10.2
± 0.3
|
7.4
± 0.2
|
1709 |
EN300-12587_3_1
|
|
CC(=O)N1CCC[C@@H]1C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.5
|
7.4
± 0.3
|
1710 |
EN300-68889_1_1
|
|
CCNC(=O)CCC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.2
± 0.3
|
7.4
± 0.2
|
1711 |
EN300-306047_3_1
|
|
Cn1cc(nn1)CCC(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.2
|
7.4
± 0.2
|
1712 |
DAR-DIA-0d514e7d-18
|
|
C[C@H]1COc2c(cc(cc2OC(F)(F)F)Cl)[C@@H]1C(=O)Nc3cncc4c3cccc4 |
−10.2
± 0.2
|
7.4
± 0.1
|
1713 |
EN300-249475_1_1
|
|
CC(=O)NC(=O)CO[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.2
± 0.2
|
7.4
± 0.2
|
1714 |
DAR-DIA-5ff57136-2_1
|
|
C[C@H]1COc2ccc(cc2[C@@H]1C(=O)N(c3cncc4c3cccc4)C(=O)C=C)Cl |
−10.2
± 0.2
|
7.4
± 0.1
|
1715 |
EN300-7429970_1_1
|
|
CS(=O)(=O)CC1CC(C1)NC(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.3
|
7.4
± 0.3
|
1716 |
EN300-226314_1_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC(=O)[C@H]5CCS(=O)(=O)C5 |
−10.2
± 0.3
|
7.4
± 0.2
|
1717 |
EN300-37195_1_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC(=O)N[C@H]5CCCCNC5=O |
−10.2
± 0.3
|
7.4
± 0.2
|
1718 |
EN300-6744028_3_8
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@H]5C[C@@H]6C[C@H]5[C@H]([C@H]6O)O |
−10.2
± 0.3
|
7.4
± 0.2
|
1719 |
EN300-359750_3_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@@H]5CCC(=O)O5 |
−10.2
± 0.3
|
7.4
± 0.2
|
1720 |
EN300-109535_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C[C@@H]5CC(=O)OC5 |
−10.2
± 0.2
|
7.4
± 0.2
|
1721 |
EN300-1911992_2_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COC[C@@H]([C@H]5CCOC5)O |
−10.2
± 0.3
|
7.4
± 0.2
|
1722 |
EN300-96159_3_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cc5[nH]ncn5 |
−10.2
± 0.3
|
7.4
± 0.2
|
1723 |
EN300-7463171_4_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCCS(=O)(=O)CCO |
−10.2
± 0.7
|
7.4
± 0.5
|
1724 |
EN300-705381_3_1
|
|
COC[C@H]1C[C@H]1C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.3
|
7.4
± 0.2
|
1725 |
EN300-95094_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CSC5 |
−10.2
± 0.2
|
7.4
± 0.1
|
1726 |
EN300-97758_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CCF |
−10.2
± 0.3
|
7.4
± 0.2
|
1727 |
EDG-MED-90036822-24
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5(COC5)F |
−10.2
± 0.3
|
7.4
± 0.2
|
1728 |
EN300-2008102_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OC[C@@H]5CN6C[C@H](O5)CCC6=O |
−10.2
± 0.3
|
7.4
± 0.2
|
1729 |
ED_-GRI-5b13fbe2-67
|
|
CN1CCc2c(cc(nn2)NCCO[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6)C1 |
−10.2
± 0.3
|
7.4
± 0.2
|
1730 |
EN300-01527_1_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC(=O)NC[C@H]5CCCO5 |
−10.2
± 0.3
|
7.4
± 0.2
|
1731 |
EN300-7457159_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCc5cc(on5)C6(COC6)O |
−10.2
± 0.3
|
7.4
± 0.2
|
1732 |
EN300-96362_1_4
|
|
C[C@H]([C@H](C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)NC(=O)C5CC5)O |
−10.2
± 0.3
|
7.4
± 0.2
|
1733 |
EN300-1608590_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCc5nc(on5)N6CCOCC6 |
−10.2
± 0.3
|
7.4
± 0.2
|
1734 |
EN300-304771_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CN5CCN(C5=O)C6CC6 |
−10.2
± 0.4
|
7.4
± 0.3
|
1735 |
EN300-6734171_1_2
|
|
C[C@]1(CCC(=O)N(C1)C)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.3
|
7.4
± 0.2
|
1736 |
EN300-50561_1_2
|
|
Cc1nnc2n1C[C@H](CC2)C(=O)N[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−10.2
± 0.2
|
7.4
± 0.2
|
1737 |
EN300-253443_3_1
|
|
CCCN1C[C@@H](CC1=O)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.3
|
7.4
± 0.2
|
1738 |
EDG-MED-90036822-103
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CC6(C5)CC(C6)CN |
−10.2
± 0.4
|
7.4
± 0.3
|
1739 |
EN300-211779_3_1
|
|
CC(=O)N1CCC[C@H]1C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.3
|
7.4
± 0.3
|
1740 |
EN300-122866_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCSC[C@@H]5C(=O)N |
−10.2
± 0.3
|
7.4
± 0.2
|
1741 |
EN300-300217_3_2
|
|
C/C=C/[C@@H](C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−10.2
± 0.3
|
7.4
± 0.2
|
1742 |
EN300-1299691_1_1
|
|
CC(C)OC[C@@H](C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)NC(=O)C |
−10.2
± 0.3
|
7.4
± 0.2
|
1743 |
EN300-1273019_1_1
|
|
CCc1[nH]c(=O)c(cn1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.3
|
7.4
± 0.2
|
1744 |
EN300-1644723_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@@H]5[C@@H]6[C@@H]5COCC6 |
−10.2
± 0.3
|
7.4
± 0.2
|
1745 |
EN300-210084_3_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C[C@H]5CCCC(=O)N5 |
−10.2
± 0.3
|
7.4
± 0.2
|
1746 |
EN300-223741_3_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5(CC5)S(=O)(=O)N |
−10.2
± 0.3
|
7.4
± 0.2
|
1747 |
EN300-140582_3_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@@H]5COCC[N@@H+]5CC(F)F |
−10.2
± 0.3
|
7.4
± 0.2
|
1748 |
EDJ-MED-fcba3f31-3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC5=NCCO5 |
−10.2
± 0.2
|
7.4
± 0.1
|
1749 |
EN300-204133_1_1
|
|
COC1(CCOCC1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.3
|
7.4
± 0.2
|
1750 |
EDG-MED-90036822-108
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C(C(CC5CC5)O)F |
−10.2
± 0.2
|
7.4
± 0.1
|
1751 |
VLA-UCB-50c39ae8-8_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@H]3CCOc4c3cc(cc4O[C@@H]5CC(=O)N5)Cl |
−10.2
± 0.2
|
7.4
± 0.1
|
1752 |
JAG-UCB-706446eb-8_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)Cc5cccc(c5)C[NH3+] |
−10.2
± 0.3
|
7.4
± 0.2
|
1753 |
EN300-1719075_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5C[C@](C6(C5)COC6)(CO)F |
−10.2
± 0.4
|
7.4
± 0.3
|
1754 |
EN300-52383_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CNC(=O)Cn5cncn5 |
−10.2
± 0.3
|
7.4
± 0.2
|
1755 |
EN300-66494_4_1
|
|
CNC(=O)NCCC(=O)NCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.2
± 0.3
|
7.4
± 0.2
|
1756 |
EN300-31845_1_1
|
|
COCCN1C[C@@H](CC1=O)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.3
|
7.4
± 0.2
|
1757 |
EN300-367383_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N[C@]56C[C@H]5COC6 |
−10.2
± 0.3
|
7.4
± 0.2
|
1758 |
EN300-1696962_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCCCn5cnnn5 |
−10.2
± 0.3
|
7.4
± 0.2
|
1759 |
EN300-12247_1_1
|
|
CC(C)(C)C(=O)NCC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.2
± 0.3
|
7.4
± 0.2
|
1760 |
KAD-UNI-8a629cb0-35
|
|
c1cc2c(c(cnc2)NC(=O)[C@]3(c4c(ccc(c4)Cl)OCC3)CCNC(=O)[C@@H]5[C@@]6(C5)C[C@H](C6)O)cc1 |
−10.2
± 0.3
|
7.4
± 0.2
|
1761 |
EN300-222120_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC[C@@](C5)(c6cn[nH]n6)O |
−10.2
± 0.4
|
7.4
± 0.3
|
1762 |
EN300-120436_1_1
|
|
Cn1[cH+][nH]n(c1=O)CC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.3
|
7.4
± 0.2
|
1763 |
EN300-6729572_2_8
|
|
C[C@H]([C@H]1C[C@H]1C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−10.2
± 0.2
|
7.4
± 0.2
|
1764 |
EN300-246423_3_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CC5(CCC5)O |
−10.2
± 0.3
|
7.4
± 0.2
|
1765 |
EN300-198515_1_2
|
|
C[C@H](C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)n5cnc(n5)C#N |
−10.2
± 0.3
|
7.4
± 0.2
|
1766 |
EN300-46832_1_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC(=O)NC[C@H]5CCOC5 |
−10.2
± 0.3
|
7.4
± 0.2
|
1767 |
EN300-204936_4_1
|
|
Cn1c(cnn1)C(=O)COCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.3
|
7.4
± 0.3
|
1768 |
EN300-99983_3_1
|
|
CNC(=O)Cc1nc(on1)COCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.5
|
7.4
± 0.3
|
1769 |
EN300-39101_3_1
|
|
CCOC(=O)N(C)CC(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.2
± 0.4
|
7.4
± 0.3
|
1770 |
EN300-140582_1_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@H]5COCC[N@H+]5CC(F)F |
−10.2
± 0.3
|
7.4
± 0.2
|
1771 |
EN300-63872_3_1
|
|
Cn1cc(cn1)CC(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.3
|
7.4
± 0.2
|
1772 |
EN300-120282_2_1
|
|
Cn1cc(nn1)COC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.2
|
7.4
± 0.2
|
1773 |
EN300-39005_3_1
|
|
CN(CC(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)C(=O)OC |
−10.2
± 0.3
|
7.4
± 0.2
|
1774 |
EN300-263085_3_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5(CC5)n6cnnn6 |
−10.2
± 0.3
|
7.4
± 0.2
|
1775 |
EN300-783124_1_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@@H]([C@H]5CCOC5)F |
−10.2
± 0.2
|
7.4
± 0.1
|
1776 |
EDG-MED-90036822-49
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)Cc5cnc[nH]5 |
−10.2
± 0.2
|
7.4
± 0.2
|
1777 |
EN300-172640_1_2
|
|
C[C@H]1[C@@H](NC(=O)O1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.2
|
7.4
± 0.2
|
1778 |
EN300-51832_3_1
|
|
Cc1cnn(c1)CC(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.3
|
7.4
± 0.2
|
1779 |
EN300-110012_3_1
|
|
CC[C@@H](C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)[NH+](C)C |
−10.2
± 0.4
|
7.4
± 0.3
|
1780 |
EN300-55744_3_2
|
|
CCCC[C@H](C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)NC(=O)N |
−10.2
± 0.5
|
7.4
± 0.4
|
1781 |
DAR-DIA-076fb6ea-5
|
|
c1ccc2c(c1)cncc2N(C#CC#N)C(=O)Cc3cccc(c3)Cl |
−10.2
± 0.4
|
7.4
± 0.3
|
1782 |
EN300-306097_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CC5(CCOCC5)n6cnnn6 |
−10.2
± 0.3
|
7.4
± 0.2
|
1783 |
EN300-300217_2_1
|
|
C/C=C\[C@@H](C(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−10.2
± 0.4
|
7.4
± 0.3
|
1784 |
EN300-89418_1_1
|
|
C[C@@](CO)(C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−10.2
± 0.3
|
7.4
± 0.3
|
1785 |
EDG-MED-971238d3-3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCO |
−10.2
± 0.1
|
7.40
± 0.10
|
1786 |
DAR-DIA-23e5a6a0-4_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@H]3CCOc4c3cc(cc4O[C@@H]5CC6(CC6)C[NH2+]5)Cl |
−10.2
± 0.3
|
7.4
± 0.2
|
1787 |
EN300-184446_3_1
|
|
Cc1ccn(c(=O)c1)CC(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.3
|
7.4
± 0.2
|
1788 |
EN300-298552_3_3
|
|
CO[C@@H]([C@H]1CCOC1)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.3
|
7.4
± 0.2
|
1789 |
EN300-108413_1_2
|
|
C[C@H](CC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)C(=O)OC |
−10.2
± 0.2
|
7.4
± 0.2
|
1790 |
EN300-93074_1_1
|
|
CN(C1CC(C1)O)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.2
|
7.4
± 0.2
|
1791 |
EN300-151298_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cc(cnc5)n6ccnn6 |
−10.2
± 0.2
|
7.4
± 0.2
|
1792 |
EN300-6505003_3_3
|
|
C[C@@H]1CC[C@H](C(=O)N1)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.3
|
7.4
± 0.2
|
1793 |
EN300-02015_1_1
|
|
COCCNC(=O)CO[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.2
± 0.3
|
7.4
± 0.2
|
1794 |
EN300-22879_1_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC(=O)N5CCCC[C@H]5C(=O)N |
−10.2
± 0.3
|
7.4
± 0.2
|
1795 |
EN300-249764_2_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@H](C5CCC5)O |
−10.2
± 0.3
|
7.4
± 0.2
|
1796 |
EN300-128463_1_1
|
|
CNC(=O)CC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.2
± 0.2
|
7.4
± 0.2
|
1797 |
EN300-220194_3_3
|
|
C[C@@H]([C@H](C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O)OC |
−10.2
± 0.3
|
7.4
± 0.2
|
1798 |
EN300-72109_2_2
|
|
CC(C)(C)OC(=O)N[C@H](CO)C(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.1
± 0.5
|
7.4
± 0.4
|
1799 |
EN300-299806_1_1
|
|
CO[C@@]1(CCCN(C1)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)CO |
−10.1
± 0.4
|
7.4
± 0.3
|
1800 |
EN300-28340_3_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCC(=O)NCC(=O)N5CCCC5 |
−10.1
± 0.3
|
7.4
± 0.2
|