Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
1601 |
EN300-7436306_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC5[C@H]6COC[C@H]6ON5 |
−10.3
± 0.2
|
7.5
± 0.1
|
1602 |
LAU-MED-88a3970a-3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@H]3CCOc4c3cc(cc4OCCCO)Cl |
−10.3
± 0.2
|
7.5
± 0.2
|
1603 |
EN300-202106_2_1
|
|
Cn1c2c(c(ccn2)C(=O)NC[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6)nn1 |
−10.3
± 0.3
|
7.5
± 0.2
|
1604 |
EN300-53395_1_1
|
|
CCS(=O)(=O)CC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.3
± 0.2
|
7.5
± 0.2
|
1605 |
EN300-120586_3_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCC(=O)NCC(F)F |
−10.3
± 0.3
|
7.5
± 0.2
|
1606 |
EN300-36911_1_1
|
|
CNC(=O)NCC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.3
± 0.2
|
7.5
± 0.1
|
1607 |
EN300-6482296_3_7
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@@H]5CO[C@H]6[C@H]5COC6 |
−10.3
± 0.3
|
7.5
± 0.2
|
1608 |
EN300-23129_3_1
|
|
CC(=O)NCCNC(=O)COCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.3
± 0.2
|
7.5
± 0.2
|
1609 |
EN300-104592_1_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CC[C@H]5CCC(=O)N5 |
−10.3
± 0.3
|
7.5
± 0.2
|
1610 |
EN300-2010317_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5C[C@H]6C[C@@H]5[C@@H](C6)O |
−10.3
± 0.3
|
7.5
± 0.2
|
1611 |
EN300-68747_3_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5(CCC5)C(=O)N |
−10.3
± 0.4
|
7.5
± 0.3
|
1612 |
EN300-6729747_3_2
|
|
Cc1nnc2n1C[C@H](C2)C(=O)NCC[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−10.3
± 0.3
|
7.5
± 0.3
|
1613 |
EN300-6505003_1_4
|
|
C[C@H]1CC[C@H](C(=O)N1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.3
± 0.3
|
7.5
± 0.2
|
1614 |
EN300-74089_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5(CCOCC5)C#N |
−10.3
± 0.3
|
7.5
± 0.2
|
1615 |
EN300-105110_1_1
|
|
Cc1cc(n[nH]1)CC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.3
± 0.2
|
7.5
± 0.2
|
1616 |
EN300-1073320_1_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@H](C5(CCC5)O)O |
−10.3
± 0.3
|
7.5
± 0.2
|
1617 |
EN300-113218_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CS[C@@H]5CCOC5=O |
−10.3
± 0.3
|
7.5
± 0.2
|
1618 |
EN300-85760_1_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@H]5CCO5 |
−10.3
± 0.2
|
7.5
± 0.2
|
1619 |
EN300-686903_1_1
|
|
CCCCS(=O)(=O)CC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.3
± 0.3
|
7.5
± 0.3
|
1620 |
EN300-11195_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC(=O)N5CCC5 |
−10.3
± 0.2
|
7.5
± 0.2
|
1621 |
EN300-1440321_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5(CCC5)S(=O)(=O)N |
−10.3
± 0.4
|
7.5
± 0.3
|
1622 |
EN300-170463_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@H]5CCOC5 |
−10.3
± 0.3
|
7.5
± 0.2
|
1623 |
EDG-MED-90036822-80
|
|
CC(C#N)C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.3
± 0.1
|
7.47
± 0.09
|
1624 |
EN300-100765_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCN6[C@@H](C5)CNC6=O |
−10.3
± 0.3
|
7.5
± 0.2
|
1625 |
EN300-101505_1_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@H]5CC(=O)N5 |
−10.3
± 0.2
|
7.5
± 0.2
|
1626 |
EDG-MED-90036822-17
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C(CF)O |
−10.3
± 0.3
|
7.5
± 0.2
|
1627 |
EN300-7433125_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@@]56C[C@@H]5[C@@H](C6)O |
−10.3
± 0.2
|
7.5
± 0.2
|
1628 |
EN300-1932013_3_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@H](CC(F)(F)F)O |
−10.3
± 0.4
|
7.5
± 0.3
|
1629 |
EN300-204419_1_1
|
|
C[C@@H](CO)N(C)C(=O)C[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.3
± 0.3
|
7.5
± 0.2
|
1630 |
EN300-25866_1_1
|
|
Cc1c(cnn1C)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.2
|
7.5
± 0.2
|
1631 |
EN300-360157_1_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C[C@]5(CCOC5)O |
−10.2
± 0.3
|
7.5
± 0.2
|
1632 |
EN300-2910941_3_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cn5cc(nn5)C(F)(F)F |
−10.2
± 0.2
|
7.5
± 0.2
|
1633 |
EN300-31969_3_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@@H]5CC(=O)N(C5)CC6CC6 |
−10.2
± 0.3
|
7.5
± 0.2
|
1634 |
EN300-149975_3_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5(CCC5)CO |
−10.2
± 0.4
|
7.5
± 0.3
|
1635 |
EDG-MED-90036822-25
|
|
Cn1cc(nc1)C(C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)F |
−10.2
± 0.2
|
7.5
± 0.1
|
1636 |
ED_-GRI-5b13fbe2-60
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCCn5cc6c(n5)CCC(C6)N |
−10.2
± 0.3
|
7.5
± 0.2
|
1637 |
EN300-31998_4_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cn[nH]n5 |
−10.2
± 0.3
|
7.5
± 0.2
|
1638 |
EN300-248883_1_1
|
|
COC[C@@]1(CCOC1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.3
|
7.5
± 0.2
|
1639 |
EN300-222357_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCCc5cn[nH]n5 |
−10.2
± 0.2
|
7.5
± 0.2
|
1640 |
EN300-51257_1_1
|
|
C[C@@H](C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)OC |
−10.2
± 0.2
|
7.5
± 0.2
|
1641 |
EN300-6482296_1_7
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@@H]5CO[C@H]6[C@H]5COC6 |
−10.2
± 0.3
|
7.5
± 0.2
|
1642 |
VLA-UCB-05e51b3f-12
|
|
c1ccc2c(c1)cncc2NC(=O)[C@]3(CCOc4c3cc(cc4OC5CC(=O)N5)Cl)CCC6CCCCC6 |
−10.2
± 0.5
|
7.5
± 0.4
|
1643 |
EN300-90142_3_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@H]5CCC[C@@H](C5)C(=O)N |
−10.2
± 0.3
|
7.5
± 0.3
|
1644 |
EN300-7423123_1_1
|
|
Cc1nc(n(n1)CC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)C |
−10.2
± 0.3
|
7.5
± 0.2
|
1645 |
EN300-69107_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC(=O)NCC5 |
−10.2
± 0.2
|
7.5
± 0.2
|
1646 |
EN300-1717166_1_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@H]5CC56CC(C6)O |
−10.2
± 0.2
|
7.5
± 0.2
|
1647 |
EN300-134855_3_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@@H](c5cccnc5)O |
−10.2
± 0.3
|
7.5
± 0.2
|
1648 |
EN300-12440_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@@H]5CC(=O)N(C5)C6CC6 |
−10.2
± 0.3
|
7.5
± 0.2
|
1649 |
EN300-19515_3_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@@H]5CCC(=O)N5 |
−10.2
± 0.2
|
7.5
± 0.2
|
1650 |
EN300-04409_1_1
|
|
COC(=O)CNC(=O)CO[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.2
± 0.2
|
7.5
± 0.2
|
1651 |
EN300-19242_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CO |
−10.2
± 0.2
|
7.5
± 0.1
|
1652 |
EN300-783124_1_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@H]([C@H]5CCOC5)F |
−10.2
± 0.2
|
7.5
± 0.2
|
1653 |
EN300-1296824_1_1
|
|
C[C@@](CC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)(COC)O |
−10.2
± 0.3
|
7.5
± 0.2
|
1654 |
EN300-89418_3_1
|
|
C[C@@](CO)(C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−10.2
± 0.5
|
7.5
± 0.3
|
1655 |
EN300-6729572_1_3
|
|
C[C@@H]([C@H]1C[C@@H]1C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−10.2
± 0.2
|
7.5
± 0.2
|
1656 |
DAR-DIA-0d514e7d-6
|
|
C[C@H]1COc2c(cc(cc2OC3CC3)Cl)[C@@H]1C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.2
|
7.5
± 0.1
|
1657 |
EN300-192482_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5[C@H]6[C@@H]5COC6 |
−10.2
± 0.3
|
7.5
± 0.2
|
1658 |
EN300-06654_3_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cn5cncn5 |
−10.2
± 0.2
|
7.5
± 0.1
|
1659 |
EN300-28177_1_2
|
|
C[C@H](C(=O)N1CCC[C@@H](C1)C(=O)N)O[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.2
|
7.5
± 0.1
|
1660 |
EN300-53423_3_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@H]5CCOC5 |
−10.2
± 0.3
|
7.5
± 0.2
|
1661 |
EN300-7434334_1_1
|
|
Cn1[cH+][nH]c2c1ncnc2C(=O)N[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−10.2
± 0.3
|
7.5
± 0.2
|
1662 |
VLA-UCB-34f3ed0c-7
|
|
c1ccc2c(c1)cncc2NC(=O)N(c3cccc(c3)Cl)C(=O)CN4CCNCC4 |
−10.2
± 0.4
|
7.5
± 0.3
|
1663 |
EN300-120414_1_1
|
|
C[C@@H]1C[N@@H+]2CC[N@H+]1C[C@@H]2C(=O)N[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−10.2
± 0.3
|
7.5
± 0.2
|
1664 |
EN300-216063_2_1
|
|
CN(C)C(=O)COC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.2
± 0.1
|
7.46
± 0.09
|
1665 |
EDG-MED-90036822-50
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)Cc5c[nH]cn5 |
−10.2
± 0.3
|
7.5
± 0.2
|
1666 |
EN300-130825_3_1
|
|
CN1[C@@H](CCC1=O)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.3
|
7.5
± 0.3
|
1667 |
EN300-62574_1_1
|
|
Cn1c(nnn1)CO[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.2
|
7.5
± 0.2
|
1668 |
EN300-64536_4_1
|
|
COCCC(=O)NCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.2
± 0.4
|
7.5
± 0.3
|
1669 |
EDG-MED-90036822-8
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C(c5c[nH]nc5)F |
−10.2
± 0.2
|
7.5
± 0.1
|
1670 |
EN300-6474220_3_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C(CCn5ccnn5)(F)F |
−10.2
± 0.5
|
7.5
± 0.3
|
1671 |
EN300-122656_3_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@@]5(CCSC5)O |
−10.2
± 0.4
|
7.5
± 0.3
|
1672 |
EN300-97697_2_1
|
|
CN(C1CC(C1)O)C(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.2
|
7.5
± 0.2
|
1673 |
EN300-101373_1_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCO[C@H](C5)CO |
−10.2
± 0.4
|
7.5
± 0.3
|
1674 |
DAR-DIA-0d514e7d-28
|
|
C[C@H]1COc2ccc(cc2[C@]1(C)C(=O)Nc3cncc4c3cccc4)Cl |
−10.23
± 0.10
|
7.45
± 0.07
|
1675 |
EN300-174668_1_1
|
|
CO[C@@]1(CCOC1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.3
|
7.4
± 0.2
|
1676 |
EN300-70431_1_1
|
|
COc1c(c(ncn1)OC)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.3
|
7.4
± 0.2
|
1677 |
EN300-97699_1_2
|
|
C[C@H](CS(=O)(=O)C)C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.2
± 0.5
|
7.4
± 0.4
|
1678 |
EN300-60831_3_1
|
|
CS(=O)(=O)C1(CCCC1)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.6
|
7.4
± 0.4
|
1679 |
EN300-6744028_1_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@@H]5C[C@@H]6C[C@H]5[C@H]([C@@H]6O)O |
−10.2
± 0.3
|
7.4
± 0.2
|
1680 |
EN300-35778_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CCC(CC5)C(=O)N |
−10.2
± 0.3
|
7.4
± 0.2
|
1681 |
EN300-206769_1_1
|
|
CS(=O)(=O)c1ccc(cn1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.3
|
7.4
± 0.2
|
1682 |
MAK-UNK-83e0a0b4-2_1
|
|
c1cc2c(cc1C[NH+]3CC[NH2+]CC3)cncc2N(CCNC4C[NH2+]C4)C(=O)[C@@H]5CCOc6c5cc(cc6)Cl |
−10.2
± 0.3
|
7.4
± 0.2
|
1683 |
EN300-212341_1_1
|
|
Cn1ccnc1COCC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.3
|
7.4
± 0.2
|
1684 |
EN300-19700_1_1
|
|
COC(=O)CO[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.22
± 0.09
|
7.45
± 0.07
|
1685 |
EN300-1081277_3_1
|
|
CNC(=O)CCC(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.2
± 0.3
|
7.4
± 0.2
|
1686 |
EN300-364992_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CC[C@H]5CC[C@H](O5)C(=O)N |
−10.2
± 0.4
|
7.4
± 0.3
|
1687 |
MAK-UNK-3875bbc8-1
|
|
Cc1ccc2c(c1)C(CCO2)C(=O)N(C)c3cncc4c3cccc4 |
−10.22
± 0.09
|
7.45
± 0.07
|
1688 |
EDG-MED-4c68219f-17
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCc5[nH]ccn5 |
−10.2
± 0.2
|
7.4
± 0.1
|
1689 |
EN300-300294_1_1
|
|
CS(=O)(=O)C[C@H]1CCCN1C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.3
|
7.4
± 0.2
|
1690 |
EN300-107267_2_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CO[C@H]5CCCNC5=O |
−10.2
± 0.2
|
7.4
± 0.1
|
1691 |
EN300-260816_1_2
|
|
CN1CC[C@H](C1=O)CO[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.3
|
7.4
± 0.2
|
1692 |
EN300-250126_3_2
|
|
CC(C)C[C@H](C(=O)N)C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.2
± 0.4
|
7.4
± 0.3
|
1693 |
EN300-73772_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCc5[nH]c(=O)[nH]n5 |
−10.2
± 0.2
|
7.4
± 0.2
|
1694 |
EN300-246440_3_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5(CC5)n6cncn6 |
−10.2
± 0.3
|
7.4
± 0.2
|
1695 |
EN300-310022_1_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@H]5C[C@@H](CN5c6ccncn6)O |
−10.2
± 0.3
|
7.4
± 0.2
|
1696 |
EN300-83864_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CCC(CC5)S(=O)(=O)N |
−10.2
± 0.4
|
7.4
± 0.3
|
1697 |
EN300-258477_3_1
|
|
C[C@@H](C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)OC |
−10.2
± 0.3
|
7.4
± 0.2
|
1698 |
EN300-30458_1_1
|
|
CN1CC[C@@H](CC1=O)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.3
|
7.4
± 0.2
|
1699 |
EN300-54541_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@H]5CCC(=O)N5 |
−10.2
± 0.2
|
7.4
± 0.2
|
1700 |
EN300-331941_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@H]5C[C@H]5C(=O)N |
−10.2
± 0.3
|
7.4
± 0.2
|