Compounds

Showing 201 through 300 of 321
Rank Compound SMILES ΔG / kcal M-1 pIC50
201 PET-UNK-94036022-4 molecule C#CC1(CC1)CS(=O)(=O)N2Cc3ccc(cc3[C@]4(C2)CC(=O)N(C4=O)c5cncc6c5cccc6)Cl −8.4 ± 0.3 6.1 ± 0.2
202 MAT-POS-853c0ffa-17 molecule CC1(CC1)CS(=O)(=O)N2Cc3ccc(cc3C4(C2)CCN(C4=O)c5cncc6c5c(ccc6)Cl)Cl −8.4 ± 0.3 6.1 ± 0.2
203 MAT-POS-b4d6b7fc-6 molecule CNC(=O)CN1Cc2ccc(cc2C3(C1)CCN(C3=O)c4cncc5c4c(ccc5)Cl)Cl −8.4 ± 0.2 6.1 ± 0.2
204 LUO-POS-868e8996-9 molecule c1ccc2c(c1)cncc2N3C(=O)C[C@@]4(C3=O)CN(Cc5c4cc(cc5)Cl)S(=O)(=O)CC6(CC6)C#N −8.3 ± 0.4 6.1 ± 0.3
205 PET-UNK-aa57768f-3 molecule C#CCN1C[C@]2(CCN(C2=O)c3cncc4c3cccc4)c5cc(ccc5C1=O)Cl −8.3 ± 0.1 6.0 ± 0.1
206 ALP-POS-4483ae88-1 molecule c1ccc2c(c1)cncc2N3CCC4(C3=O)CNS(=O)(=O)c5c4cc(cc5)Cl −8.3 ± 0.1 6.02 ± 0.08
207 PET-UNK-94036022-5 molecule c1ccc2c(c1)cncc2N3C(=O)C[C@@]4(C3=O)CN(Cc5c4cc(cc5)Cl)S(=O)(=O)CC6(CC6)Cl −8.2 ± 0.3 6.0 ± 0.2
208 EDJ-MED-fd8ed875-5 molecule CNC(=O)CN1CC2(c3cc(ccc3C1=O)Cl)C(=CN(C2=O)c4cncc5c4cccc5)F −8.2 ± 0.3 6.0 ± 0.2
209 MAT-POS-50a80394-1 molecule CC1CN(C(=O)C12CN(Cc3c2cc(cc3)Cl)S(=O)(=O)CC4(CC4)C#N)c5cncc6c5cccc6 −8.2 ± 0.4 6.0 ± 0.3
210 EDJ-MED-5cd3920d-1 molecule c1cc2cncc(c2cc1OC(F)F)N3CCC4(C3=O)CN(Cc5c4cc(cc5)Cl)S(=O)(=O)CC6(CC6)C#N −8.2 ± 0.4 6.0 ± 0.3
211 MAT-POS-853c0ffa-5 molecule c1cc2cncc(c2c(c1)Cl)N3CCC4(C3=O)CN(Cc5c4cc(cc5)Cl)S(=O)(=O)CC6(CC6)C#N −8.2 ± 0.5 6.0 ± 0.3
212 EDJ-MED-dfa1d800-3 molecule CNC(=O)C1(CC1)N2CC3(CCN(C3=O)c4cncc5c4cc(cc5)OCCN6CCS(=O)(=O)CC6)c7cc(ccc7C2=O)Cl −8.2 ± 0.3 6.0 ± 0.2
213 VLA-UNK-f702bf1c-3 molecule c1ccc2c(c1)cncc2N3C(=O)[C@@]4(CCOc5c4cc(cc5)Cl)N(C3=O)Cc6nc[nH]n6 −8.2 ± 0.2 5.9 ± 0.1
214 LUO-POS-ed2cfb03-2 molecule CNS(=O)(=O)N1Cc2ccc(cc2C3(C1)CCN(C3=O)c4cncc5c4cccc5)Cl −8.1 ± 0.4 5.9 ± 0.3
215 JOH-MSK-1f2dff76-2 molecule CNC(=O)CN1Cc2ccc(cc2[C@]3(C1)CC(=O)N(C3=O)c4cncc5c4cccc5)Cl −8.1 ± 0.3 5.9 ± 0.2
216 EDJ-MED-94fddcec-7 molecule CS(=O)(=O)Nc1ccc2c(c1)cncc2N3CCC4(C3=O)CCS(=O)(=O)c5c4cc(cc5)Cl −8.1 ± 0.2 5.9 ± 0.1
217 MAT-POS-69786b79-1 molecule CNC(=O)C1(CC1)N2Cc3ccc(cc3C4(C2)CCN(C4=O)c5cncc6c5cccc6)Cl −8.1 ± 0.2 5.9 ± 0.1
218 MAT-POS-576f7758-1 molecule CNC(=O)C1(CC1)N2Cc3ccc(cc3C4(C2)CCN(C4=O)c5cncc6c5cccc6)Cl −8.1 ± 0.2 5.9 ± 0.1
219 LUO-POS-868e8996-8 molecule CNC(=O)CN1C[C@]2(CC(=O)N(C2=O)c3cncc4c3cccc4)c5cc(ccc5C1=O)Cl −8.1 ± 0.1 5.89 ± 0.08
220 MAT-POS-853c0ffa-13 molecule c1cc2cncc(c2cc1F)N3CCC4(C3=O)CN(Cc5c4cc(cc5)Cl)S(=O)(=O)CC6(CC6)C#N −8.1 ± 0.4 5.9 ± 0.3
221 VLA-UNK-f702bf1c-7 molecule c1ccc2c(c1)cncc2N3C(=O)[C@@]4(CCOc5c4cc(cc5)Cl)N(C3=O)CCN6CCNCC6 −8.1 ± 0.2 5.9 ± 0.2
222 MIK-ENA-5d9157e9-1 molecule c1ccc2c(c1)cncc2N3CC[C@@]4(C3=O)CN(Cc5c4cc(cc5)Cl)S(=O)(=O)CC6(CC6)C#N −8.1 ± 0.4 5.9 ± 0.3
223 EDG-MED-b1ef7fe3-1 molecule CNC(=O)CN1CC2(CCN(C2=O)c3cncc4c3cc(cc4)Cl)c5cc(ccc5C1=O)Cl −8.0 ± 0.2 5.8 ± 0.2
224 PET-UNK-94036022-11 molecule C#CC1(CC1)CS(=O)(=O)N2Cc3ccc(cc3C4(C2)CC(=O)N(C4=O)c5cncc6c5cccc6)Cl −8.0 ± 0.3 5.8 ± 0.2
225 PET-UNK-aa57768f-8 molecule c1ccc2c(c1)cncc2N3CCC4(C3=O)CN(C(=O)c5c4cc(cc5)Cl)CC#N −8.0 ± 0.2 5.8 ± 0.1
226 EDJ-MED-94fddcec-4 molecule c1ccc2c(c1)cncc2N3CCC4(C3=O)CCS(=O)(=O)c5c4cc(cc5)Cl −8.0 ± 0.1 5.80 ± 0.09
227 MAT-POS-c2d406ed-4 molecule CN1C(=S)N(C(=O)C12CN(Cc3c2cc(cc3)Cl)S(=O)(=O)CC4(CC4)C#N)c5cncc6c5cccc6 −7.9 ± 0.3 5.8 ± 0.2
228 MAT-POS-983b399a-2 molecule c1ccc2c(c1)cncc2N3CCC4(C3)CCOc5c4cc(cc5)Cl −7.89 ± 0.09 5.75 ± 0.06
229 EDJ-MED-159244ea-2 molecule c1ccc2c(c1)cncc2N3CC[C@@]4(C3)CCOc5c4cc(cc5)Cl −7.86 ± 0.09 5.73 ± 0.07
230 MAT-POS-1bed62cf-3 molecule CNC(=O)CN1Cc2ccc(cc2C3(C1)CC(=O)N(C3=O)c4cncc5c4cccc5)Cl −7.8 ± 0.3 5.7 ± 0.2
231 EDJ-MED-a6bab6fb-1 molecule Cc1cccc2c1c(cnc2)N3CCC4(C3)CCOc5c4cc(cc5)Cl −7.79 ± 0.09 5.68 ± 0.07
232 VLA-UNK-56836b69-5 molecule c1ccc2c(c1)cncc2N3C(=O)[C@@]4(CC(=O)Nc5c4cc(c(c5)Cl)Cl)NC3=O −7.8 ± 0.1 5.66 ± 0.08
233 EDJ-MED-98c0a822-1 molecule CNC(=O)C1(CCC1)N2CC3(CCN(C3=O)c4cncc5c4cccc5)c6cc(ccc6S2(=O)=O)Cl −7.8 ± 0.6 5.7 ± 0.4
234 VLA-UNK-f2612802-2 molecule CNC(=O)CN1C[C@]2(CCN(C2=O)c3cncc4c3cccc4)c5cc(c(cc5S1(=O)=O)F)Cl −7.8 ± 0.2 5.7 ± 0.2
235 PET-UNK-94036022-7 molecule CNC(=O)CN1Cc2ccc(cc2[C@]3(C1)C(=O)C(=C)N(C3=O)c4cncc5c4cccc5)Cl −7.7 ± 0.3 5.6 ± 0.2
236 VLA-UNK-56836b69-3 molecule CN1C(=O)N(C(=O)[C@@]12CCOc3c2cc(c(c3)Cl)Cl)c4cncc5c4cccc5 −7.74 ± 0.08 5.64 ± 0.06
237 MAT-POS-50a80394-3 molecule CC(C)C1CN(C(=O)C12CN(Cc3c2cc(cc3)Cl)S(=O)(=O)CC4(CC4)C#N)c5cncc6c5cccc6 −7.7 ± 0.4 5.6 ± 0.3
238 ALP-POS-ecbed2ba-15 molecule c1ccc2c(c1)cncc2N3CCC4(C3=O)CN(Cc5c4cc(cc5)Cl)S(=O)(=O)CC6(CCCC6)C#N −7.7 ± 0.4 5.6 ± 0.3
239 MAT-POS-38eb6498-5 molecule CNC(=O)CN1Cc2ccc(cc2C3(C1)CCN(C3=O)c4cncc5c4cc(cc5)C(=O)NC)Cl −7.6 ± 0.2 5.6 ± 0.2
240 MAT-POS-c7726e07-6 molecule CNC(=O)CN1Cc2ccc(cc2[C@@]3(C1)CCN(C3=O)c4cncc5c4cccc5)Cl −7.6 ± 0.2 5.6 ± 0.1
241 MAT-POS-40ad851a-2 molecule CCN(C)CCOc1ccc2cncc(c2c1)N3CCC4(C3=O)CN(Cc5c4cc(cc5)Cl)S(=O)(=O)CC6(CC6)C#N −7.6 ± 0.8 5.5 ± 0.6
242 MAT-POS-38eb6498-6 molecule CNC(=O)CN1CC2(CCN(C2=O)c3cncc4c3cc(cc4)C(=O)NC)c5cc(ccc5C1=O)Cl −7.6 ± 0.2 5.5 ± 0.2
243 LUO-POS-868e8996-12 molecule CNC(=O)CN1Cc2ccc(cc2[C@@]3(C1)CCN(C3=O)c4cncc5c4cccc5)Cl −7.6 ± 0.2 5.5 ± 0.1
244 MAT-POS-1bed62cf-1 molecule c1ccc2c(c1)cncc2N3C(=O)CC4(C3=O)CN(Cc5c4cc(cc5)Cl)S(=O)(=O)CC6(CC6)C#N −7.6 ± 0.4 5.5 ± 0.3
245 MAT-POS-69786b79-2 molecule c1ccc2c(c1)cncc2N3CCC4(C3=O)CN(Cc5c4cc(cc5)Cl)CC(=O)NC6CC6 −7.6 ± 0.2 5.5 ± 0.2
246 EDJ-MED-d7486dd1-1 molecule Cc1cc(cc2c1c(cnc2)N3CCC4(C3)CCOc5c4cc(cc5)Cl)S(=O)(=O)C −7.6 ± 0.1 5.5 ± 0.1
247 ALP-POS-afe0272e-2 molecule CNC(=O)CN1CC2(CCN(C2=O)c3cncc4c3cccc4)c5cc(c(cc5C1=O)Cl)Cl −7.6 ± 0.2 5.5 ± 0.1
248 ALP-POS-ecbed2ba-7 molecule CNC(=O)C1(CC1)N2Cc3ccc(cc3C4(C2)CCN(C4=O)c5cncc6c5cccc6)Cl −7.6 ± 0.2 5.5 ± 0.2
249 EDJ-MED-94fddcec-5 molecule CS(=O)(=O)c1ccc2c(c1)cncc2N3CCC4(C3=O)CCS(=O)(=O)c5c4cc(cc5)Cl −7.5 ± 0.2 5.5 ± 0.1
250 MAT-POS-c7726e07-5 molecule CNC(=O)CN1Cc2ccc(cc2[C@]3(C1)CCN(C3=O)c4cncc5c4cccc5)Cl −7.5 ± 0.2 5.5 ± 0.1
251 MAT-POS-983b399a-3 molecule c1ccc2c(c1)cncc2N3CC4(CCOc5c4cc(cc5)Cl)CC3=O −7.47 ± 0.06 5.44 ± 0.04
252 PET-UNK-94036022-12 molecule c1ccc2c(c1)cncc2N3C(=O)CC4(C3=O)CN(Cc5c4cc(cc5)Cl)S(=O)(=O)CC6(CC6)Cl −7.5 ± 0.3 5.4 ± 0.2
253 EDJ-MED-8bb691af-7 molecule CNC(=O)CN1CC2(CCN(C2)c3cncc4c3cccc4)c5cc(ccc5C1=O)Cl −7.4 ± 0.1 5.42 ± 0.10
254 EDJ-MED-ee81482e-2 molecule CN1CC(C1)Oc2ccc3cncc(c3c2)N4CCC5(C4=O)CN(Cc6c5cc(cc6)Cl)S(=O)(=O)CC7(CC7)C#N −7.4 ± 0.5 5.4 ± 0.4
255 EDJ-MED-8bb691af-4 molecule CNC(=O)CN1Cc2ccc(cc2C3(C1)CCN(C3=O)c4cncc5c4cccc5)Cl −7.4 ± 0.2 5.4 ± 0.1
256 MAT-POS-69786b79-3 molecule CC1(CC1)NC(=O)CN2Cc3ccc(cc3C4(C2)CCN(C4=O)c5cncc6c5cccc6)Cl −7.4 ± 0.3 5.4 ± 0.2
257 LUO-POS-868e8996-10 molecule c1ccc2c(c1)cncc2N3C(=O)C[C@]4(C3=O)CN(Cc5c4cc(cc5)Cl)S(=O)(=O)CC6(CC6)C#N −7.2 ± 0.4 5.3 ± 0.3
258 ALP-POS-ecbed2ba-14 molecule c1ccc2c(c1)cncc2N3CCC4(C3=O)CN(Cc5c4cc(cc5)Cl)CC(=O)NCC#N −7.2 ± 0.2 5.3 ± 0.1
259 LUO-POS-868e8996-11 molecule CNC(=O)CN1Cc2ccc(cc2[C@]3(C1)CCN(C3=O)c4cncc5c4cccc5)Cl −7.2 ± 0.2 5.3 ± 0.1
260 VLA-MRT-a639d434-2 molecule c1ccc2c(c1)cncc2N3C(=O)[C@@]4(CN(Cc5c4cc(cc5)Cl)CC(=O)N)NC3=O −7.2 ± 0.2 5.3 ± 0.2
261 PET-UNK-77d5678a-4 molecule c1ccc2c(c1)cncc2N3C(=O)CC4(C3=O)CN(Cc5c4cc(cc5)Cl)Cc6nncs6 −7.2 ± 0.2 5.2 ± 0.1
262 ALP-POS-ecbed2ba-12 molecule c1ccc2c(c1)cncc2N3CCC4(C3=O)CN(Cc5c4cc(cc5)Cl)CC(=O)NCC6CC6 −7.2 ± 0.2 5.2 ± 0.2
263 EDJ-MED-94fddcec-6 molecule CN(c1ccc2c(c1)cncc2N3CCC4(C3=O)CCS(=O)(=O)c5c4cc(cc5)Cl)S(=O)(=O)C −7.1 ± 0.2 5.2 ± 0.2
264 EDJ-MED-e78d5f1a-1 molecule c1cc2cncc(c2c(c1)Cl)N3CCC4(C3)CCOc5c4cc(cc5)Cl −7.1 ± 0.1 5.19 ± 0.09
265 LUO-POS-b4dec3be-1 molecule CNC(=O)CN1Cc2ccc(cc2[C@@]3(C1)CCN(C3=O)c4cncc5c4cc(cc5)F)Cl −7.1 ± 0.2 5.2 ± 0.1
266 MAT-POS-69786b79-4 molecule c1ccc2c(c1)cncc2N3CCC4(C3=O)CN(Cc5c4cc(cc5)Cl)CC(=O)NC6(CC6)C#N −7.1 ± 0.3 5.2 ± 0.2
267 VLA-UNK-f2612802-1 molecule CNC(=O)CN1C([C@]2(CCN(C2=O)c3cncc4c3cccc4)c5cc(ccc5S1(=O)=O)Cl)C(F)(F)F −7.0 ± 0.4 5.1 ± 0.3
268 LUO-POS-eaf50f21-1 molecule c1ccc2c(c1)cncc2N3C(=O)C4(CN(Cc5c4cc(cc5)Cl)S(=O)(=O)CC6(CC6)C#N)N=C3N −7.0 ± 0.4 5.1 ± 0.3
269 ALP-POS-ecbed2ba-8 molecule c1ccc2c(c1)cncc2N3CCC4(C3=O)CN(Cc5c4cc(cc5)Cl)S(=O)(=O)CC6(CCC6)C#N −7.0 ± 0.6 5.1 ± 0.4
270 VLA-MRT-a639d434-1 molecule CNC(=O)CN1Cc2ccc(cc2[C@@]3(C1)C(=O)N(C(=O)N3)c4cncc5c4cccc5)Cl −7.0 ± 0.2 5.1 ± 0.1
271 ALP-POS-ecbed2ba-17 molecule CN(CC#N)S(=O)(=O)N1Cc2ccc(cc2C3(C1)CCN(C3=O)c4cncc5c4cccc5)Cl −7.0 ± 0.7 5.1 ± 0.5
272 PET-UNK-77d5678a-1 molecule c1ccc2c(c1)cncc2N3C(=O)C[C@@]4(C3=O)CN(Cc5c4cc(cc5)Cl)Cc6nncs6 −6.9 ± 0.2 5.1 ± 0.1
273 MAT-POS-853c0ffa-18 molecule CC1(CC1)CS(=O)(=O)N2Cc3ccc(cc3C4(C2)CCN(C4=O)c5cncc6c5c(cc(c6)F)Cl)Cl −6.9 ± 0.3 5.0 ± 0.2
274 MAT-POS-b4d6b7fc-5 molecule CNC(=O)CN1Cc2ccc(cc2C3(C1)CCN(C3=O)c4cncc5c4cc(cc5)F)Cl −6.8 ± 0.2 4.9 ± 0.1
275 EDJ-MED-5cd3920d-6 molecule c1ccc2c(c1)cncc2N3CCC4(C3=O)CN(Cc5c4cc(cc5)Cl)S(=O)(=O)CC6(CC6)C(F)(F)F −6.8 ± 0.5 4.9 ± 0.3
276 VLA-MRT-8c78ee15-3 molecule CNC(=O)CN1Cc2ccc(cc2[C@]3(C1)C(=O)N(C(=O)N3)c4cncc5c4cccc5)Cl −6.8 ± 0.2 4.9 ± 0.2
277 VLA-MRT-8c78ee15-4 molecule c1ccc2c(c1)cncc2N3C(=O)[C@]4(CN(Cc5c4cc(cc5)Cl)CC(=O)N)NC3=O −6.8 ± 0.2 4.9 ± 0.1
278 JOH-MSK-b735e33c-1 molecule c1ccc2c(c1)cncc2N3C(=O)[C@@]4(CCOc5c4cc(c(c5)Cl)Cl)N(C3=O)CC6CCC(=O)NC6 −6.6 ± 0.2 4.8 ± 0.1
279 ALP-POS-afe0272e-1 molecule CNC(=O)CN1Cc2cc(c(cc2C3(C1)CCN(C3=O)c4cncc5c4cccc5)Cl)Cl −6.6 ± 0.2 4.8 ± 0.2
280 EDJ-MED-d4864bdc-3 molecule c1ccc2c(c1)cncc2N3CCC4(C3=O)CCS(=O)(=O)c5c4cc(cc5)Cl −6.6 ± 0.2 4.8 ± 0.2
281 MAT-POS-50a80394-7 molecule CC1(CN(C(=O)C12CN(Cc3c2cc(cc3)Cl)CC(=O)NC)c4cncc5c4cccc5)C −6.6 ± 0.3 4.8 ± 0.2
282 JOH-MSK-1f2dff76-1 molecule CNC(=O)CN1Cc2ccc(cc2[C@@]3(C1)CC(=O)N(C3=O)c4cncc5c4cccc5)Cl −6.5 ± 0.3 4.7 ± 0.2
283 JOH-MSK-51c67e7d-1 molecule CN1Cc2ccc(cc2[C@@]3(C1)CC(=O)N(C3=O)c4cncc5c4cccc5)Cl −6.3 ± 0.1 4.62 ± 0.08
284 MAT-POS-50a80394-8 molecule CC1(CN(C(=O)C12CN(Cc3c2cc(cc3)Cl)S(=O)(=O)CC4(CC4)C#N)c5cncc6c5cccc6)C −6.3 ± 0.6 4.6 ± 0.5
285 LUO-POS-ed2cfb03-1 molecule CN1CCN(CC1)S(=O)(=O)N2Cc3ccc(cc3C4(C2)CCN(C4=O)c5cncc6c5cccc6)Cl −6.3 ± 0.9 4.6 ± 0.7
286 ALP-POS-41e2080f-1 molecule c1ccc2c(c1)cncc2N3CCC4(C3=O)CCS(=O)(=O)c5c4cc(cc5)Cl −6.3 ± 0.2 4.6 ± 0.2
287 JOH-MSK-51c67e7d-2 molecule CN1Cc2ccc(cc2[C@]3(C1)CC(=O)N(C3=O)c4cncc5c4cccc5)Cl −6.3 ± 0.2 4.6 ± 0.1
288 VLA-MRT-8c78ee15-1 molecule c1ccc2c(c1)cncc2N3C(=O)C4(CNCc5c4cc(cc5)Cl)NC3=O −6.3 ± 0.2 4.6 ± 0.1
289 EDJ-MED-f3cfbbb5-1 molecule Cc1cccc2c1c(cnc2)N3CCC4(C3)COCc5c4cc(cc5)Cl −6.24 ± 0.08 4.54 ± 0.06
290 VLA-MRT-a639d434-3 molecule c1ccc2c(c1)cncc2N3C(=O)[C@@]4(CNCc5c4cc(cc5)Cl)NC3=O −6.1 ± 0.2 4.4 ± 0.1
291 ALP-POS-ecbed2ba-22 molecule c1ccc2c(c1)cncc2N3CCC4(C3=O)CN(Cc5c4cc(cc5)Cl)S(=O)(=O)CC6(CC6)CC#N −6.0 ± 0.5 4.3 ± 0.3
292 JOH-MSK-949975c8-1 molecule c1ccc2c(c1)cncc2N3C(=O)C4(CN(Cc5c4cc(cc5)Cl)S(=O)(=O)CC6(CC6)C#N)N(C3=O)CC7CCC(=O)NC7 −5.9 ± 0.3 4.3 ± 0.2
293 EDG-MED-00af8776-1 molecule c1ccc2c(c1)cncc2N3C=NC4(C3=O)CN(Cc5c4cc(cc5)Cl)S(=O)(=O)CC6(CC6)C#N −5.9 ± 0.4 4.3 ± 0.3
294 VLA-MRT-8c78ee15-2 molecule c1ccc2c(c1)cncc2N3C(=O)[C@]4(CNCc5c4cc(cc5)Cl)NC3=O −5.8 ± 0.2 4.2 ± 0.1
295 ALP-POS-ecbed2ba-1 molecule CC1(CS(=O)(=O)C1)CS(=O)(=O)N2Cc3ccc(cc3C4(C2)CCN(C4=O)c5cncc6c5cccc6)Cl −5.8 ± 0.5 4.2 ± 0.4
296 LUO-POS-eaf50f21-5 molecule CCNC1=NC2(CN(Cc3c2cc(cc3)Cl)S(=O)(=O)CC4(CC4)C#N)C(=O)N1c5cncc6c5cccc6 −5.7 ± 0.4 4.1 ± 0.3
297 LUO-POS-eaf50f21-3 molecule CC(=O)NC1=NC2(CN(Cc3c2cc(cc3)Cl)S(=O)(=O)CC4(CC4)C#N)C(=O)N1c5cncc6c5cccc6 −5.4 ± 0.5 4.0 ± 0.4
298 EDJ-MED-159244ea-3 molecule c1ccc2c(c1)cncc2N3C[C@@]4(CCOc5c4cc(cc5)Cl)CC3=O −5.44 ± 0.09 3.96 ± 0.07
299 JOH-MSK-cef8a2bc-1 molecule c1ccc2c(c1)cncc2N3C(=O)C4(CN(Cc5c4cc(c(c5)Cl)Cl)S(=O)(=O)CC6(CC6)C#N)N(C3=O)CC7CCC(=O)NC7 −5.4 ± 0.3 3.9 ± 0.2
300 JOH-MSK-1f2dff76-4 molecule c1ccc2c(c1)cncc2N3C(=O)C[C@@]4(C3=O)CNCc5c4cc(cc5)Cl −5.3 ± 0.1 3.9 ± 0.1
Last updated 2022-01-14T23:27:52.194393+00:00
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