Rank |
Microstate |
SMILES |
ΔG / kcal M-1 |
101 |
MAT-POS-be048f2c-5_1
|
|
CCn1c(ccn1)C(=O)N2Cc3ccc(cc3[C@]4(C2)CCN(C4=O)c5cncc6c5cccc6)Cl |
−8.5
± 0.2
|
102 |
ALP-POS-ecbed2ba-16_4
|
|
C[N@](CCC#N)S(=O)(=O)[N@]1Cc2ccc(cc2[C@]3(C1)CCN(C3=O)c4cncc5c4cccc5)Cl |
−8.5
± 0.5
|
103 |
EDJ-MED-976a33d5-1_1
|
|
CNC(=O)C1(CC1)N2C[C@]3(CCN(C3=O)c4cncc5c4cccc5)c6cc(ccc6C2=O)Cl |
−8.5
± 0.1
|
104 |
MAT-POS-40ad851a-1_3
|
|
C[N@@H+]1CCC[C@H]1COc2ccc3cncc(c3c2)N4CC[C@@]5(C4=O)C[N@@](Cc6c5cc(cc6)Cl)S(=O)(=O)CC7(CC7)C#N |
−8.4
± 0.5
|
105 |
PET-UNK-aa57768f-7_1
|
|
c1ccc2c(c1)cncc2N3CC[C@@]4(C3=O)CN(C(=O)c5c4cc(cc5)Cl)Cc6nnco6 |
−8.3
± 0.1
|
106 |
JOH-MSK-1f2dff76-2_1
|
|
CNC(=O)C[N@@H+]1Cc2ccc(cc2[C@]3(C1)CC(=O)N(C3=O)c4cncc5c4cccc5)Cl |
−8.3
± 0.3
|
107 |
MAT-POS-38eb6498-6_1
|
|
CNC(=O)CN1C[C@]2(CCN(C2=O)c3cncc4c3cc(cc4)C(=O)NC)c5cc(ccc5C1=O)Cl |
−8.3
± 0.1
|
108 |
EDJ-MED-8bb691af-5_2
|
|
c1ccc2c(c1)cncc2N3C[C@]4(CC3=O)C[N@](Cc5c4cc(cc5)Cl)S(=O)(=O)CC6(CC6)C#N |
−8.3
± 0.3
|
109 |
LUO-POS-8484f2d3-2_1
|
|
C[NH+](C)CCOc1ccc2cncc(c2c1)N3CC[C@@]4(C3=O)C[N@@](Cc5c4cc(cc5)Cl)S(=O)(=O)CC6(CC6)C#N |
−8.3
± 0.6
|
110 |
EDJ-MED-9f4ac58c-7_1
|
|
COC1(CC1)CS(=O)(=O)N2C[C@]3(CCN(C3=O)c4cncc5c4ccc(c5)NS(=O)(=O)C)c6cc(ccc6C2=O)Cl |
−8.3
± 0.4
|
111 |
EDJ-MED-cc48ee33-2_1
|
|
Cn1c(ccn1)C(=O)N2C[C@]3(CCN(C3=O)c4cncc5c4cccc5)c6cc(ccc6C2=O)Cl |
−8.2
± 0.2
|
112 |
EDJ-MED-b6c6ee2b-3_2
|
|
COc1ccc2cncc(c2c1)N3CC[C@@]4(C3=O)C[N@](Cc5c4cc(cc5)Cl)S(=O)(=O)CC6(CC6)C#N |
−8.2
± 0.5
|
113 |
EDJ-MED-5cd3920d-4_1
|
|
CNC(=O)C1(CC1)N2C[C@]3(CCN(C3=O)c4cncc5c4cc(cc5)C(F)F)c6cc(ccc6C2=O)Cl |
−8.2
± 0.2
|
114 |
ALP-POS-ecbed2ba-18_4
|
|
CC[N@](C)S(=O)(=O)[N@]1Cc2ccc(cc2[C@]3(C1)CCN(C3=O)c4cncc5c4cccc5)Cl |
−8.2
± 0.5
|
115 |
EDJ-MED-b6c6ee2b-4_2
|
|
c1cc2cncc(c2cc1Cl)N3CC[C@@]4(C3=O)C[N@](Cc5c4cc(cc5)Cl)S(=O)(=O)CC6(CC6)C#N |
−8.2
± 0.3
|
116 |
ALP-POS-ecbed2ba-21_3
|
|
C[N@@](CCOC)S(=O)(=O)[N@]1Cc2ccc(cc2[C@]3(C1)CCN(C3=O)c4cncc5c4cccc5)Cl |
−8.2
± 0.6
|
117 |
JOH-MSK-51c67e7d-1_1
|
|
C[N@@H+]1Cc2ccc(cc2[C@]3(C1)CC(=O)N(C3=O)c4cncc5c4cccc5)Cl |
−8.2
± 0.1
|
118 |
MAT-POS-50a80394-4_2
|
|
C[C@H]1CN(C(=O)[C@@]12C[N@@H+](Cc3c2cc(cc3)Cl)CC(=O)NC)c4cncc5c4cccc5 |
−8.1
± 0.3
|
119 |
EDJ-MED-9f4ac58c-1_1
|
|
c1cc2c(cc1Cl)cncc2N3CC[C@@]4(C3=O)CN(C(=O)c5c4cc(cc5)Cl)S(=O)(=O)CC6(CC6)C#N |
−8.1
± 0.4
|
120 |
MAT-POS-50a80394-3_3
|
|
CC(C)[C@@H]1CN(C(=O)[C@@]12C[N@](Cc3c2cc(cc3)Cl)S(=O)(=O)CC4(CC4)C#N)c5cncc6c5cccc6 |
−8.1
± 0.5
|
121 |
ALP-POS-ecbed2ba-1_2
|
|
CC1(CS(=O)(=O)C1)CS(=O)(=O)[N@]2Cc3ccc(cc3[C@]4(C2)CCN(C4=O)c5cncc6c5cccc6)Cl |
−8.1
± 0.5
|
122 |
PET-UNK-aa57768f-1_1
|
|
c1ccc2c(c1)cncc2N3CC[C@@]4(C3=O)CN(C(=O)c5c4cc(cc5)Cl)Cc6nnco6 |
−8.1
± 0.2
|
123 |
EDJ-MED-fed7ac0b-2_1
|
|
CNC(=O)C1(CC1)N2C[C@]3(CNN(C3=O)c4cncc5c4cccc5)c6cc(ccc6C2=O)Cl |
−8.1
± 0.1
|
124 |
MAT-POS-40ad851a-5_2
|
|
c1cc2cncc(c2cc1OCCC[NH+]3CCCC3)N4CC[C@@]5(C4=O)C[N@](Cc6c5cc(cc6)Cl)S(=O)(=O)CC7(CC7)C#N |
−8.1
± 0.5
|
125 |
EDJ-MED-b6c6ee2b-7_1
|
|
CNC(=O)C1(CC1)N2C[C@]3(CCN(C3=O)c4cncc5c4cc(cc5)F)c6cc(ccc6C2=O)Cl |
−8.1
± 0.2
|
126 |
ALP-POS-ecbed2ba-21_4
|
|
C[N@](CCOC)S(=O)(=O)[N@]1Cc2ccc(cc2[C@]3(C1)CCN(C3=O)c4cncc5c4cccc5)Cl |
−8.1
± 0.5
|
127 |
PET-UNK-14142a25-1_1
|
|
CNC(=O)CN1C[C@]2(CCN(C2=O)c3cncc4c3cccc4)c5cc(ccc5C1=O)Cl |
−8.1
± 0.1
|
128 |
MAT-POS-be048f2c-6_1
|
|
CC(C)n1c(ccn1)C(=O)N2Cc3ccc(cc3[C@]4(C2)CCN(C4=O)c5cncc6c5cccc6)Cl |
−8.0
± 0.3
|
129 |
MAT-POS-853c0ffa-14_2
|
|
COC1(CC1)CS(=O)(=O)[N@]2Cc3ccc(cc3[C@]4(C2)CCN(C4=O)c5cncc6c5cc(cc6)F)Cl |
−8.0
± 0.3
|
130 |
LUO-POS-b5068a05-2_2
|
|
c1ccc2c(c1)cncc2N3C(=O)[C@@]4(C[N@](Cc5c4cc(cc5)Cl)S(=O)(=O)CC6(CC6)C#N)N=C3NC#N |
−8.0
± 0.3
|
131 |
EDJ-MED-ee81482e-2_2
|
|
C[NH+]1CC(C1)Oc2ccc3cncc(c3c2)N4CC[C@@]5(C4=O)C[N@](Cc6c5cc(cc6)Cl)S(=O)(=O)CC7(CC7)C#N |
−8.0
± 0.4
|
132 |
EDJ-MED-ee81482e-2_1
|
|
C[NH+]1CC(C1)Oc2ccc3cncc(c3c2)N4CC[C@@]5(C4=O)C[N@@](Cc6c5cc(cc6)Cl)S(=O)(=O)CC7(CC7)C#N |
−8.0
± 0.4
|
133 |
LUO-POS-d1147590-1_1
|
|
C[NH+]1CCC(CC1)Oc2ccc3cncc(c3c2)N4CC[C@@]5(C4=O)C[N@@](Cc6c5cc(cc6)Cl)S(=O)(=O)CC7(CC7)C#N |
−8.0
± 0.5
|
134 |
EDJ-MED-7e491f08-2_1
|
|
CNC(=O)C1(CC1)N2C[C@]3(c4cc(ccc4C2=O)Cl)C(=O)N(CC3(F)F)c5cncc6c5cccc6 |
−8.0
± 0.2
|
135 |
EDJ-MED-cc48ee33-7_1
|
|
Cn1c(ccn1)CN2C[C@]3(CCN(C3=O)c4cncc5c4cccc5)c6cc(ccc6C2=O)Cl |
−7.9
± 0.2
|
136 |
MAT-POS-38eb6498-4_1
|
|
CNC(=O)CN1C[C@]2(CCN(C2=O)c3cncc4c3cc(cc4)OCC[NH+](C)C)c5cc(ccc5C1=O)Cl |
−7.9
± 0.3
|
137 |
EDJ-MED-ee81482e-1_1
|
|
c1cc2cncc(c2cc1OC3C[NH2+]C3)N4CC[C@@]5(C4=O)C[N@@](Cc6c5cc(cc6)Cl)S(=O)(=O)CC7(CC7)C#N |
−7.9
± 0.4
|
138 |
JOH-MSK-1f2dff76-3_1
|
|
c1ccc2c(c1)cncc2N3C(=O)C[C@@]4(C3=O)C[NH2+]Cc5c4cc(cc5)Cl |
−7.9
± 0.2
|
139 |
JOH-MSK-51c67e7d-2_1
|
|
C[N@@H+]1Cc2ccc(cc2[C@]3(C1)CC(=O)N(C3=O)c4cncc5c4cccc5)Cl |
−7.9
± 0.1
|
140 |
LUO-POS-8c3e556a-1_1
|
|
CNC(=O)CN1C[C@]2(CCN(C2=O)c3cncc4c3cc(cc4)Cl)c5cc(ccc5C1=O)Cl |
−7.9
± 0.1
|
141 |
EDJ-MED-fed7ac0b-1_1
|
|
CNC(=O)CN1C[C@]2(CNN(C2=O)c3cncc4c3cccc4)c5cc(ccc5C1=O)Cl |
−7.8
± 0.2
|
142 |
MAT-POS-576f7758-2_1
|
|
CNC(=O)C1(CC1)N2C[C@]3(CCN(C3=O)c4cncc5c4cccc5)c6cc(ccc6C2=O)Cl |
−7.8
± 0.2
|
143 |
JOH-MSK-51c67e7d-2_2
|
|
C[N@H+]1Cc2ccc(cc2[C@]3(C1)CC(=O)N(C3=O)c4cncc5c4cccc5)Cl |
−7.8
± 0.1
|
144 |
MAT-POS-40ad851a-2_2
|
|
CC[N@H+](C)CCOc1ccc2cncc(c2c1)N3CC[C@@]4(C3=O)C[N@@](Cc5c4cc(cc5)Cl)S(=O)(=O)CC6(CC6)C#N |
−7.7
± 0.7
|
145 |
EDJ-MED-5cd3920d-2_2
|
|
c1cc2cncc(c2cc1C(F)F)N3CC[C@@]4(C3=O)C[N@](Cc5c4cc(cc5)Cl)S(=O)(=O)CC6(CC6)C#N |
−7.7
± 0.4
|
146 |
MAT-POS-50a80394-3_4
|
|
CC(C)[C@H]1CN(C(=O)[C@@]12C[N@](Cc3c2cc(cc3)Cl)S(=O)(=O)CC4(CC4)C#N)c5cncc6c5cccc6 |
−7.7
± 0.5
|
147 |
EDJ-MED-dfa1d800-4_1
|
|
CNC(=O)C1(CC1)N2C[C@]3(CCN(C3=O)c4cncc5c4cc(cc5)OCC[NH+]6CCC(CC6)(F)F)c7cc(ccc7C2=O)Cl |
−7.7
± 0.3
|
148 |
JOH-MSK-51c67e7d-1_2
|
|
C[N@H+]1Cc2ccc(cc2[C@]3(C1)CC(=O)N(C3=O)c4cncc5c4cccc5)Cl |
−7.67
± 0.10
|
149 |
LUO-POS-9931618f-1_1
|
|
CNC(=O)CN1C[C@]2(CCN(C2=O)c3cncc4c3cccc4)c5cc(ccc5C1=O)Cl |
−7.6
± 0.1
|
150 |
ALP-POS-ecbed2ba-15_1
|
|
c1ccc2c(c1)cncc2N3CC[C@@]4(C3=O)C[N@@](Cc5c4cc(cc5)Cl)S(=O)(=O)CC6(CCCC6)C#N |
−7.6
± 0.4
|
151 |
EDG-MED-b1ef7fe3-3_1
|
|
CNC(=O)CN1C[C@]2(CCN(C2=O)c3cncc4c3ccc(c4)F)c5cc(ccc5C1=O)Cl |
−7.6
± 0.1
|
152 |
ALP-POS-ecbed2ba-3_1
|
|
CC1(CC1)CS(=O)(=O)[N@@]2Cc3ccc(cc3[C@]4(C2)CCN(C4=O)c5cncc6c5cccc6)Cl |
−7.6
± 0.2
|
153 |
LUO-POS-8c3e556a-2_1
|
|
CNC(=O)CN1C[C@]2(CCN(C2=O)c3cncc4c3cc(cc4)Cl)c5cc(ccc5C1=O)Cl |
−7.5
± 0.1
|
154 |
EDJ-MED-976a33d5-2_1
|
|
CNC(=O)C1(CC1)N2C[C@]3(CCN(C3=O)c4cncc5c4ccc(c5)S(=O)(=O)C)c6cc(ccc6C2=O)Cl |
−7.5
± 0.2
|
155 |
EDJ-MED-9f4ac58c-2_1
|
|
c1ccc2c(c1)cncc2N3CC[C@@]4(C3=O)CN(C(=O)c5c4cc(cc5)Cl)S(=O)(=O)CC6(CC6)C#N |
−7.5
± 0.4
|
156 |
EDJ-MED-fd8ed875-6_1
|
|
CNC(=O)C1(CC1)N2C[C@@]3(c4cc(ccc4C2=O)Cl)C(=CN(C3=O)c5cncc6c5cccc6)F |
−7.5
± 0.2
|
157 |
LUO-POS-9931618f-2_1
|
|
CNC(=O)CN1C[C@]2(CCN(C2=O)c3cncc4c3cccc4)c5cc(ccc5C1=O)Cl |
−7.5
± 0.2
|
158 |
JOH-MSK-1f2dff76-4_1
|
|
c1ccc2c(c1)cncc2N3C(=O)C[C@@]4(C3=O)C[NH2+]Cc5c4cc(cc5)Cl |
−7.5
± 0.2
|
159 |
EDJ-MED-9f4ac58c-6_1
|
|
COC1(CC1)CS(=O)(=O)N2C[C@]3(CCN(C3=O)c4cncc5c4cccc5)c6cc(ccc6C2=O)Cl |
−7.5
± 0.4
|
160 |
EDJ-MED-ede5c6cb-2_1
|
|
c1cc2c(cc1NS(=O)(=O)C3CC3)cncc2N4CC[C@@]5(C4=O)CCS(=O)(=O)c6c5cc(cc6)Cl |
−7.5
± 0.2
|
161 |
MAT-POS-50a80394-1_3
|
|
C[C@@H]1CN(C(=O)[C@@]12C[N@](Cc3c2cc(cc3)Cl)S(=O)(=O)CC4(CC4)C#N)c5cncc6c5cccc6 |
−7.4
± 0.3
|
162 |
EDJ-MED-b6c6ee2b-6_1
|
|
CNC(=O)CN1C[C@]2(CCN(C2=O)c3cncc4c3cc(cc4)F)c5cc(ccc5C1=O)Cl |
−7.4
± 0.2
|
163 |
MAT-POS-1d5ab790-3_1
|
|
CNC(=O)CN1C[C@]2(CCN(C2=O)c3cncc4c3c(ccc4)Cl)c5cc(ccc5C1=O)Cl |
−7.4
± 0.1
|
164 |
LUO-POS-ed2cfb03-1_1
|
|
C[NH+]1CCN(CC1)S(=O)(=O)[N@@]2Cc3ccc(cc3[C@]4(C2)CCN(C4=O)c5cncc6c5cccc6)Cl |
−7.4
± 0.3
|
165 |
PET-UNK-aa57768f-9_1
|
|
C#CCN1C[C@]2(CCN(C2=O)c3cncc4c3cccc4)c5cc(ccc5C1=O)Cl |
−7.4
± 0.1
|
166 |
EDJ-MED-fed7ac0b-4_1
|
|
CNC(=O)CN1C[C@]2(C=NN(C2=O)c3cncc4c3cccc4)c5cc(ccc5C1=O)Cl |
−7.4
± 0.1
|
167 |
MAT-POS-50a80394-6_4
|
|
CC(C)[C@H]1CN(C(=O)[C@@]12C[N@H+](Cc3c2cc(cc3)Cl)CC(=O)NC)c4cncc5c4cccc5 |
−7.4
± 0.3
|
168 |
EDG-MED-b1ef7fe3-2_1
|
|
CNC(=O)CN1C[C@]2(CCN(C2=O)c3cncc4c3cc(cc4)F)c5cc(ccc5C1=O)Cl |
−7.4
± 0.1
|
169 |
EDJ-MED-98c0a822-4_1
|
|
CNC(=O)C1(COC1)N2C[C@]3(CCN(C3=O)c4cncc5c4cccc5)c6cc(ccc6C2=O)Cl |
−7.3
± 0.2
|
170 |
MAT-POS-50a80394-6_2
|
|
CC(C)[C@H]1CN(C(=O)[C@@]12C[N@@H+](Cc3c2cc(cc3)Cl)CC(=O)NC)c4cncc5c4cccc5 |
−7.3
± 0.2
|
171 |
MAT-POS-40ad851a-3_2
|
|
CC[NH+](CC)CCOc1ccc2cncc(c2c1)N3CC[C@@]4(C3=O)C[N@](Cc5c4cc(cc5)Cl)S(=O)(=O)CC6(CC6)C#N |
−7.3
± 0.7
|
172 |
EDJ-MED-dfa1d800-1_1
|
|
CNC(=O)C1(CC1)N2C[C@]3(CCN(C3=O)c4cncc5c4cc(cc5)OCC[NH+]6CCCC6)c7cc(ccc7C2=O)Cl |
−7.3
± 0.3
|
173 |
PET-UNK-aa57768f-3_1
|
|
C#CCN1C[C@]2(CCN(C2=O)c3cncc4c3cccc4)c5cc(ccc5C1=O)Cl |
−7.3
± 0.2
|
174 |
MAT-POS-50a80394-5_2
|
|
CC[C@H]1CN(C(=O)[C@@]12C[N@@H+](Cc3c2cc(cc3)Cl)CC(=O)NC)c4cncc5c4cccc5 |
−7.3
± 0.2
|
175 |
BRU-THA-73c97d88-1_1
|
|
c1ccc2c(c1)cncc2N3C(=O)[C@@]4(CCOc5c4cc(cc5)Cl)C=N3 |
−7.3
± 0.1
|
176 |
EDG-MED-b1ef7fe3-1_1
|
|
CNC(=O)CN1C[C@]2(CCN(C2=O)c3cncc4c3cc(cc4)Cl)c5cc(ccc5C1=O)Cl |
−7.3
± 0.2
|
177 |
PET-UNK-7e9559de-4_2
|
|
c1ccc2c(c1)cncc2N3CC[C@@]4(C3=O)C[N@H+](Cc5c4cc(cc5)Cl)Cc6nncs6 |
−7.2
± 0.2
|
178 |
DAR-DIA-0f7b7cd9-8_1
|
|
c1ccc2c(c1)cncc2N3C(=O)[C@@]4(CCOc5c4cc(cc5)Cl)C(=O)S3 |
−7.2
± 0.1
|
179 |
ALP-POS-ecbed2ba-17_1
|
|
C[N@@](CC#N)S(=O)(=O)[N@@]1Cc2ccc(cc2[C@]3(C1)CCN(C3=O)c4cncc5c4cccc5)Cl |
−7.2
± 0.2
|
180 |
DAR-DIA-6be260fc-5_1
|
|
c1ccc2c(c1)cncc2N3CC[C@@]4(C3=O)CCNc5c4cc(cc5)Cl |
−7.2
± 0.1
|
181 |
ALP-POS-ecbed2ba-2_2
|
|
c1ccc2c(c1)cncc2N3CC[C@@]4(C3=O)C[N@](Cc5c4cc(cc5)Cl)S(=O)(=O)CC6(CCS(=O)(=O)CC6)C#N |
−7.2
± 0.4
|
182 |
EDJ-MED-fd8ed875-4_1
|
|
CNC(=O)C1(CC1)N2C[C@]3(C=CN(C3=O)c4cncc5c4cccc5)c6cc(ccc6C2=O)Cl |
−7.1
± 0.2
|
183 |
PET-UNK-94036022-10_2
|
|
c1ccc2c(c1)cncc2N3CC[C@@]4(C3=O)C[N@](Cc5c4cc(cc5)Cl)S(=O)(=O)CC6(CC6)Cl |
−7.1
± 0.4
|
184 |
EDG-MED-b1ef7fe3-4_1
|
|
CNC(=O)CN1C[C@]2(CCN(C2=O)c3cncc4c3ccc(c4)Cl)c5cc(ccc5C1=O)Cl |
−7.1
± 0.2
|
185 |
ALP-POS-ecbed2ba-6_1
|
|
COC1(CC1)CS(=O)(=O)[N@@]2Cc3ccc(cc3[C@]4(C2)CCN(C4=O)c5cncc6c5cccc6)Cl |
−7.1
± 0.3
|
186 |
MAT-POS-853c0ffa-21_1
|
|
CC1(CC1)CS(=O)(=O)[N@@]2Cc3ccc(cc3[C@]4(C2)CCN(C4=O)c5cncc6c5cc(cc6)F)Cl |
−7.1
± 0.3
|
187 |
MAT-POS-983b399a-1_1
|
|
c1ccc2c(c1)cncc2N3CC[C@@]4(C3=O)CCOc5c4cc(cc5)Cl |
−7.1
± 0.1
|
188 |
MAT-POS-853c0ffa-12_1
|
|
CC(C)(c1ccc2cncc(c2c1)N3CC[C@@]4(C3=O)C[N@@](Cc5c4cc(cc5)Cl)S(=O)(=O)CC6(CC6)OC)O |
−7.1
± 0.4
|
189 |
EDJ-MED-468565e0-1_1
|
|
c1cc2cncc(c2cc1OCC[NH+]3CCCC3)N4CC[C@@]5(C4=O)C[N@@](Cc6c5cc(cc6)Cl)S(=O)(=O)CC7(CC7)C#N |
−7.1
± 0.4
|
190 |
ALP-POS-ecbed2ba-18_3
|
|
CC[N@@](C)S(=O)(=O)[N@]1Cc2ccc(cc2[C@]3(C1)CCN(C3=O)c4cncc5c4cccc5)Cl |
−7.1
± 0.6
|
191 |
BRU-THA-55eab31a-1_1
|
|
c1ccc2c(c1)cncc2N3C(=O)[C@@]4(CCNc5c4cc(cc5)Cl)C=N3 |
−7.1
± 0.1
|
192 |
PET-UNK-aa57768f-8_1
|
|
c1ccc2c(c1)cncc2N3CC[C@@]4(C3=O)CN(C(=O)c5c4cc(cc5)Cl)CC#N |
−7.0
± 0.1
|
193 |
ALP-POS-ecbed2ba-19_4
|
|
C[N@](CCO)S(=O)(=O)[N@]1Cc2ccc(cc2[C@]3(C1)CCN(C3=O)c4cncc5c4cccc5)Cl |
−7.0
± 0.8
|
194 |
LUO-POS-ed2cfb03-2_2
|
|
CNS(=O)(=O)[N@]1Cc2ccc(cc2[C@]3(C1)CCN(C3=O)c4cncc5c4cccc5)Cl |
−7.0
± 0.4
|
195 |
MAT-POS-50a80394-6_1
|
|
CC(C)[C@@H]1CN(C(=O)[C@@]12C[N@@H+](Cc3c2cc(cc3)Cl)CC(=O)NC)c4cncc5c4cccc5 |
−7.0
± 0.3
|
196 |
MAT-POS-38eb6498-3_2
|
|
CNC(=O)C[N@H+]1Cc2ccc(cc2[C@]3(C1)CCN(C3=O)c4cncc5c4cc(cc5)OCC[NH+](C)C)Cl |
−7.0
± 0.3
|
197 |
MIK-ENA-5d9157e9-2_2
|
|
c1ccc2c(c1)cncc2N3CC[C@@]4(C3=O)C[N@](Cc5c4cc(cc5)Cl)S(=O)(=O)CC6(CC6)C#N |
−7.0
± 0.5
|
198 |
EDJ-MED-fd8ed875-5_1
|
|
CNC(=O)CN1C[C@@]2(c3cc(ccc3C1=O)Cl)C(=CN(C2=O)c4cncc5c4cccc5)F |
−7.0
± 0.1
|
199 |
EDJ-MED-8bb691af-8_1
|
|
CNC(=O)CN1C[C@]2(CCN(C2=O)c3cncc4c3cccc4)c5cc(ccc5C1=O)Cl |
−7.0
± 0.2
|
200 |
EDJ-MED-cc48ee33-5_1
|
|
Cc1cc(n(n1)C)C(=O)N2Cc3ccc(cc3[C@]4(C2)CCN(C4=O)c5cncc6c5cccc6)Cl |
−7.0
± 0.2
|